Unable to install on some systems

For some odd reason lately I've run into a few systems where I just simply can't install SuRun at all. The installer simply exits without any errors or anything that I can find. In fact, it's as if it never runs at all. The executable will appear in the task list for a few moments then simply go away. I never see a window or anything to indicate that it even was trying to start. No new entries appear in the system logs nor any other indicator that I could find whatsoever of problems. In the past I've had issues with some things that violate DEP simply exiting like this without a window (even though you're supposed to get an error message informing you if this happens) so I tried adding the installer to the exceptions list to not use DEP, but this didn't help either. I can't think of any unique factors in the setups of the systems that do work versus those that do not either. I've installed SuRun successfully on one system that was nLite optimized and yet it would fail on another that was just a pure copy of Windows straight from the original CD, but then I'll see another nLite optimized system fail while a pure copy will work.

Does the installer have any known dependencies that I might perhaps not be meeting correctly?